List of Publications in Malaria and Tuberculosis Divisions
LIST OF PUBLICATIONS IN MALARIA DIVISION (2003-2012)
2012
• Julien Zwang , Jean-Louis Ndiaye, Abdoulaye Djimdé, Grant Dorsey, Andreas Mårtensson, Corine Karema and Piero Olliaro. Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa- Malaria Journal,2012, 54(8):1080-90
• Lorenz von Seidlein, Rasaq Olaosebikan, Ilse C. E. Hendriksen,4 Sue J. Lee,Olanrewaju Timothy Adedoyin, Tsiri Agbenyega, Samuel Blay Nguah, Kalifa Bojang, Jacqueline L. Deen, Jennifer Evans, Caterina I. Fanello, Ermelinda Gomes, Alínia José Pedro, Catherine Kahabuka,Corine Karema, Esther Kivaya, Kathryn Maitland,1Olugbenga A. Mokuolu, George Mtove, Juliet Mwanga-Amumpaire,13 Behzad Nadjm, Margaret Nansumba, Wirichada Pan Ngum, Marie A. Onyamboko,Hugh Reyburn, Tharisara Sakulthaew, Kamolrat Silamut, Antoinette K. Tshefu, Noella Umulisa, Samwel Gesase, Nicholas P. J. Day, Nicholas J. White, and Arjen M. Dondorp . Predicting the clinical outcome of severe falciparum malaria in african children : findings from a large randomized trial- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012, 11:25
2011
• A twine D, Balikagala B, Bassat Q, Chalwe V, D’Alessandro U, Dhorda M, Donegan S, Garner P, González R, Tinga Guiguemde R, Hachizovu S, Kajungu D, Kamya M, Karema C, Kibuuka A, Kremsner PG, Lell B, Machevo S, Menéndez C, Menten J, Meremikwu M, Mombo-Ngoma G, Mudangha F, Mulenga M, Munyaneza T, Nabasumba C, Nambozi M, Odey F, Okello S, Oringange C, Oyo-Ita A, Piola P, Ravinetto R, Tinto H, Rouamba N, Strecker F, Talisuna AO, Umulisa N, Uwimana A, Valéa I, Van Geertruyden JP, van Loen H, Williamson P, Yeka A . A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children : a randomized trial-Plos- Med,2011, 8(11):e1001119
• Zeile I, Gahutu JB, Shyirambere C, Steininger C, Musemakweri A, Sebahungu F, Karema C, Harms G, Eggelte TA, Mockenhaupt FP. Molecular markers of Plasmodium falciparum drug resistance in southern highland Rwanda- Acta Tropica, 2011, 121(1):50-4
• Dorsey G, Karema C, Mårtensson A, Ndiaye JL, Sirima SB, Vaillant M, Zwang J Olliaro P, Djimdé A.Hematologic parameters in pediatric uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa- The American journal of Tropical medecine and Hygiene,2011, ;85(4):619-25 .
• Gahutu JB, Steininger C, Shyirambere C, Zeile I, Cwinya-Ay N, Danquah I, Larsen CH, Eggelte TA, Uwimana A, Karema C, Musemakweri A, Harms G, Mockenhaupt FP. Prevalence and risk factors of malaria among children in southern highland Rwanda- Malaria Journal, 2011, 10:134
• Olliaro P, Djimdé A, Karema C, Mårtensson A, Ndiaye JL, Sirima SB, Dorsey G, Zwang J. Standardised versus actual white cell counts in estimating thick film parasitaemia in African children under five- Tropical Medecine and International Health,2011, 16(5):551-4
2010
• Arjen M Dondorp,l Caterina I Fanello,l Ilse CE Hendriksen,l Ermelinda Gomes,a Amir Seni,a Kajal D Chhaganlal,a Kalifa Bojang,b Rasaq Olaosebikan,b Nkechinyere Anunobi,b Kathryn Maitland,d Esther Kivaya,d Tsiri Agbenyega,c Samuel Blay Nguah,c Jennifer Evans,c Samwel Gesase,e Catherine Kahabuka,e George Mtove,g Behzad Nadjm,f Jacqueline Deen,f Juliet Mwanga-Amumpaire,j Margaret Nansumba,j Corine Karema,h Noella Umulisa,h Aline Uwimana,h Olugbenga A Mokuolu,i Olanrewaju T Adedoyin,i Wahab BR Johnson,i Antoinette K Tshefu,k Marie A Onyamboko,k Tharisara Sakulthaew,l Wirichada Pan Ngum,l Kamolrat Silamut,l Kasia Stepniewska,l Charles J Woodrow,l Delia Bethell,m Bridget Wills,o Martina Oneko,p Tim E Peto, m Lorenz von Seidlein,n Nicholas PJ Day,l Nicholas J White,l. Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT) : an open-label, randomised trial- The Lancet,2O10, 376(9753):1647-57
• Kayitare E, Vervaet C, Mehuys E, Kayumba PC, Ntawukulilyayo JD, Karema C, Bortel V, Remon JP. Taste-masked quinine pamoate tablets for treatment of children with uncomplicated Plasmodium falciparum malaria- International Journal of Pharmaceutics, 2010, 392(1-2):29-34 .
• Karema C, Imwong M, Fanello CI, Stepniewska K, Uwimana A, Nakeesathit S, Dondorp A, Day NP, White NJ.( 2010)Molecular correlates of high-level antifolate resistance in Rwandan children with Plasmodium falciparum malaria- Antimicrobial agent and Chemotherapy,2010, 54(1):477-83.
2009
• Zwang J, Olliaro P, Barennes H, Bonnet M, Brasseur P, Bukirwa H, Cohuet S, D’Alessandro U, Djimdé A, Karema C, Guthmann JP, Hamour S, Ndiaye JL, Mårtensson A, Rwagacondo C, Sagara I, Same-Ekobo A, Sirima SB, van den Broek I, Yeka A, Taylor WR, Dorsey G, Randrianarivelojosia M. Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa : a multi-centre analysis- Malaria Journal,2009 , 8:203 .
• Rulisa S, Mens PF, Karema C, Schallig HD, Kaligirwa N, Vyankandondera J, de Vries PJ. Malaria has no effect on birth weight in Rwanda- Malaria Journal, 2009, 8:194 .
• Zwang J, Ashley EA, Karema C, D’Alessandro U, Smithuis F, Dorsey G, Janssens B, Mayxay M, Newton P, Singhasivanon P, Stepniewska K, White NJ, Nosten F.Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria : a prospective multi-centre individual patient data analysis- Plos Med, 2009, 4(7):e6358
• Sagara I, Rulisa S, Mbacham W, Adam I, Sissoko K, Maiga H, Traore OB, Dara N, Dicko YT, Dicko A, Djimdé A, Jansen FH, Doumb. Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa : a randomized multi-centre trial- Malaria Journal,2009 ;8:63.
• Otten M, Aregawi M, Were W, Karema C, Medin A, Bekele W, Jima D, Gausi K, Komatsu R, Korenromp E, Low-Beer D, Grabowsky M. Initial evidence of reduction of malaria cases and deaths in Rwanda and Ethiopia due to rapid scale-up of malaria prevention and treatment- Malaria Journal,2009 , 8:14.
2008
• Fanello CI, Karema C, Avellino P, Bancone G, Uwimana A, Lee SJ, d’Alessandro U, Modiano D. High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency- Plos Med, 2008, 3(12):e4031.
• Culleton RL, Mita T, Ndounga M, Unger H, Cravo PV, Paganotti GM, Takahashi N, Kaneko A, Eto H, Tinto H, Karema C, D’Alessandro U, do Rosário V, Kobayakawa T, Ntoumi F, Carter R,Tanabe K. Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing- Malaria Journal, 2008, 7:174 .
• Sievers AC, Lewey J, Musafiri P, Franke MF, Bucyibaruta BJ, Stulac SN, Rich ML, Karema C, Daily JP. Reduced paediatric hospitalizations for malaria and febrile illness patterns following implementation of community-based malaria control programme in rural Rwanda- Malaria Journal, 2008,7:167.
• Fanello CI, Karema C, Ngamije D, Uwimana A, Ndahindwa V, Van Overmeir C, Van Doren W, Curtis J, D’Alessandro U. A randomised trial to assess the efficacy and safety of chlorproguanil/dapsone + artesunate for the treatment of uncomplicated Plasmodium falciparum malaria- Transactions of the Royal society of Tropical Medicine and Hygiene, 2008, 102(5):412-20.
2007
• Rulisa S, Gatarayiha JP, Kabarisa T, Ndayisaba G (2007) Comparison of different artemisinin-based combinations for the treatment of Plasmodium falciparum malaria in children in Kigali, Rwanda, an area of resistance to sulfadoxine-pyrimethamine : artesunate plus sulfadoxine/pyrimethamine versus artesunate plus sulfamethoxypyrazine/pyrimethamine- The American journal of Tropical medecine and Hygiene, 2007, 77(4):612-6.
• Fanello CI, Karema C, van Doren W, Van Overmeir C, Ngamije D, D’Alessandro U . A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda- Transactions of the Royal society of Tropical Medicine and Hygiene, 2007, 101(4):344-50
2006
• Karema C, Fanello CI, van Overmeir C, van Geertruyden JP, van Doren W, Ngamije D, D’Alessandro U. Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children- Transactions of the Royal society of Tropical Medicine and Hygiene, 2006 , 100(12):1105-11
• Tinto H, Rwagacondo C, Karema C, Mupfasoni D, Vandoren W, Rusanganwa E, Erhart A, Van Overmeir C, Van Marck E, D’Alessandro U In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda- Transactions of the Royal society of Tropical Medicine and Hygiene, 2006, 100(6):509-14
• Fanello CI, Karema C, van Doren W, Rwagacondo CE, D’Alessandro U Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults- Tropical Medecine and International Health, 2006, 11(5):589-96 .
2005
• Tinto H, Rwagacondo C, Karema C, Mupfasoni D, Vandoren W, Rusanganwa E, Erhart A, Van Overmeir C, Van Marck E, D’Alessandro U. In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda- Transactions of the Royal society of Tropical Medicine and Hygiene, 2005, 100(6):509-14.
• Van Geertruyden JP, Ntakirutimana D, Erhart A, Rwagacondo C, Kabano A, D’Alessandro U. Malaria infection among pregnant women attending antenatal clinics in six Rwandan districts- Tropical Medecine and International Health, 2005, 10(7):681-8.
2004
• Rwagacondo CE, Karema C, Mugisha V, Erhart A, Dujardin JC, Van Overmeir C, Ringwald P, D’Alessandro U . Is amodiaquine failing in Rwanda ? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria- Tropical Medecine and International Health, 2004, (10):1091-8 .
2003
• Rwagacondo CE, Niyitegeka F, Sarushi J, Karema C, Mugisha V, Dujardin JC, Van Overmeir C, van den Ende J, D’Alessandro U . Efficacy of amodiaquine alone and combined with sulfadoxine-pyrimethamine and of sulfadoxine pyrimethamine combined with artesunate- The American journal of Tropical medecine and Hygiene, 2003, 68(6):743-7.
LIST OF PUBLICATIONS IN TB DIVISION (2006-2012)
2011
• Pevzner ES, Vandebriel G, Lowrance DW, Gasana M, Finlay A Evaluation of the rapid scale-up of collaborative TB/HIV activities in TB facilities in Rwanda, 2005-2009 - BMC Public Health, 2011, 11- 550.
• Uwizeye CB, De Serres G, Gilca R, Schwartzman K, Gasana M Tuberculosis may be underestimated in Rwandan women- Int J Tuberc Lung Dis, 2011, 15(6)- 776-81.
• Lorent N, Sebatunzi O, Mukeshimana G, Van den Ende J, Clerinx J Incidence and risk factors of serious adverse events during antituberculous treatment in Rwanda : a prospective cohort study- PLoS One, 2011, 6(5), e19566.
• Franke MF, Robins JM, Mugabo J, Kaigamba F, Cain LE, Fleming JG, Murray MB. Effectiveness of early antiretroviral therapy initiation to improve survival among HIV-infected adults with tuberculosis : a retrospective cohort study- PLoS Med, 2011, 8(5), e1001029.
2010
• Jef Van den Ende PhD, Julie Mugabekazi MD, Juan Moreira MD, Eric Seryange MD, Paulin Basinga MD, Zeno Bisoffi MD, Joris Menten MSc and Marleen Boelaert PhD. Effect of applying a treatment threshold in a population. An example of pulmonary tuberculosis in Rwanda- J Eval Clin Pract , 2010, 16(3), 499-508
• Tuyisenge L, Ndimubanzi CP, Ndayisaba G, Muganga N, Menten J, Boelaert M, Van den Ende J. Evaluation of latent class analysis and decision thresholds to guide the diagnosis of pediatric tuberculosis in a Rwandan reference hospital- Pediatr Infect Dis J, 2010, 29(2), e11-8.
• Claude Mambo Muvunyi, Florence Masaisa , Claude Bayingana1, Andre Musemakweri, Leon Mutesa and Teresa Carbonell Hernandez. 4Prevalence and diagnostic aspects of sputum smear positive tuberculosis cases at a tertiary care institution in Rwanda- African Journal of Microbiology Research, 2010, Vol. 4(1)-088-091
• Moreira J, Bisig B, Muwawenimana P, Basinga P, Bisoffi Z, Haegeman F, Kishore P, Van den, Ende J. Weighing Harm in therapeutic decisions of smear-negative pulmonary tuberculosis- Med Decis Making, 2010, 29(3), 380-90
2009
• Gasana M, Vandebriel G, Kabanda G, Tsiouris SJ, Justman J, Sahabo R, Kamugundu D, El-Sadr WM . Integrating tuberculosis and HIV care in rural Rwanda - Int J Tuberc Lung Dis , 2009, 12(3 Suppl 1), 39-43.
2008
• Mugabekazi Julie, Boelaert Marleen, Sarushi Joseph, Seruyange Eric, Basinga Paulin, Musemakweli André, Van der Stuyft Patrick, Bisoffi Zeno, Moreira Juan, Van Den Ende Jef. Accuracy of Clinical Signs in the Diagnosis of Pulmonary Tuberculosis : Comparison of Three Reference Standards Using Data from a Tertiary Care Centre in Rwanda- The Open Tropical Medicine Journal, 2008, 1
• Lorent N, Mugwaneza P, Mugabekazi J, Gasana M, Van Bastelaere S, Clerinx J, Van den Ende J. Risk factors for delay in the diagnosis and treatment of tuberculosis at a referral hospital in Rwanda- Int J Tuberc Lung Dis , 2008, 12(4), 392-6.
• Umubyeyi A, Rigouts L, Shamputa IC, Dediste A, Struelens M, Portaels F. Low levels of second-line drug resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Rwanda- Int J Infect Dis, 2008, 12(2), 152-6
• Umubyeyi A, Shamputa IC, Rigouts L, Dediste A, Struelens M, Portaels F. Evidence of ’amplifier effect’ in pulmonary multidrug-resistant tuberculosis : report of three cases- Int J Infect Dis , 2008, 11(6), 508-12
2007
• Ngang PN, Ntaganira J, Kalk A, Wolter S, Ecks S. Perceptions and beliefs about cough and tuberculosis and implications for TB control in rural Rwanda- Int J Tuberc Lung Dis, 2007, 11(10), 1108-13.
• Quezada CM, Kamanzi E, Mukamutara J, De Rijk P, Rigouts L, Portaels F, Ben Amor Y.(2010) Implementation validation performed in Rwanda to determine whether the INNO-LiPA Rif.TB line probe assay can be used for detection of multidrug-resistant Mycobacterium tuberculosis in low-resource countries- J Clin Microbiol , 2007, 45(9)- 3111-4
• Umubyeyi AN, Shamputa IC, Rigouts L, Dediste A, Karita E, Struelens MJ, Portaels F.Molecular investigation of recurrent tuberculosis in patients from Rwanda- Int J Tuberc Lung Dis, 2007, 11(8), 860-7.
• Umubyeyi AN, Rigouts L, Shamputa IC, Fissette K, Elkrim Y, de Rijk PW, Struelens MJ. Portaels FLimited fluoroquinolone resistance among Mycobacterium tuberculosis isolates from Rwanda : results of a national survey- J Antimicrob Chemother, 2007, 59(5), 1031-3
• Umubyeyi AN, Rigouts L, Zissis G, Kamanzi E, Pauwels P, Gasana M, Vandebriel G, Struelens M, Portaels F. Primary and acquired resistance to antituberculous drugs in strains of Mycobacterium tuberculosis isolated in Rwanda- Med Trop (Mars), 2007, 67(2), 149-53.
• Umubyeyi AN, Vandebriel G, Gasana M, Basinga P, Zawadi JP, Gatabazi J, Pauwels P, Nzabintwali F, Nyiramasarabwe L, Fissette K, Rigouts L, Struelens MJ, Portaels F. (2011 )Results of a national survey on drug resistance among pulmonary tuberculosis patients in Rwanda- Int J Tuberc Lung Dis, 2007, 11(2), 189-94 .
• Basinga P, Moreira J, Bisoffi Z, Bisig B, Van den Ende J. (2011) Why are clinicians reluctant to treat smear-negative tuberculosis ? An inquiry about treatment thresholds in Rwanda - Med Decis Making, 2007, 27(1), 53-60.
2006
• Umubyeyi AN, Martin A, Zissis G, Struelens M, Karita E, Portaels F. Evaluation of the resazurin-microtiter assay for rapid detection of ofloxacin resistance in M. Tuberculosis- Int J Tuberc Lung Dis, 2006 10(7)- 808-11.
